The main objective of the study was a pharmacological review of the bioactive constituents of the above mentioned tree nuts, as effective supplements and natural medicinal foods in Alzheimer’s Disease (AD) patients.
PubMed and ScienceDirect databases were used to search AD-related researches on these tree nuts from year 2000 to present. Results showed that almonds, hazelnuts and walnuts provide macronutrients, micronutrients, and phytochemicals which may affect several pathways in AD pathogenesis, such as oxidative stress, cholesterol lowering and anti-inflammatory properties, among others.
These nuts have been recommended for their brain-protective activity and particularly reversing brain atrophy in the case of hazelnut. The study concluded that the use of these tree nuts could be more considered in scientific researches as effective nutrients for prevention or even management of AD, thanks to their nutritional composition, specially to their phytochemicals content.
Gorji, N., Moeini, R., & Memariani, Z. (2017). Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer’s disease: a neuropharmacological review of their bioactive constituents. Pharmacological research. DOI:10.1016/j.phrs.2017.12.003
PubMed and ScienceDirect databases were used to search AD-related researches on these tree nuts from year 2000 to present. Results showed that almonds, hazelnuts and walnuts provide macronutrients, micronutrients, and phytochemicals which may affect several pathways in AD pathogenesis, such as oxidative stress, cholesterol lowering and anti-inflammatory properties, among others.
These nuts have been recommended for their brain-protective activity and particularly reversing brain atrophy in the case of hazelnut. The study concluded that the use of these tree nuts could be more considered in scientific researches as effective nutrients for prevention or even management of AD, thanks to their nutritional composition, specially to their phytochemicals content.
Gorji, N., Moeini, R., & Memariani, Z. (2017). Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer’s disease: a neuropharmacological review of their bioactive constituents. Pharmacological research. DOI:10.1016/j.phrs.2017.12.003