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Products: Peanuts

Impact of age on adherence and efficacy of peanut oral-immunotherapy using a standardized protocol.

Authors: Zhu, R., Robertson, Protudjer, J., Macikunas, A., Kim, R., Jeimy, S., Kim, H.
  • Journals: Pediatr Allergy Immunol
  • Pages:
  • Year: 2021
Peanut oral immunotherapy (POIT) has been shown to be an effective therapy in peanut allergic children, as it improves food allergy-related quality of life [1-2] . Randomized controlled trials and observational, real world studies have shown that POIT may be effective and safe in children of all ages, although starting POIT at a younger age may be more efficacious and safer [3,5, 8] . Furthermore, initiation of POIT at a younger age may have higher rates of sustained unresponsiveness [3] . However, there has not been formal evaluation of this concept, using a standardized protocol [6] . The aim of our study was to examine associations between the age at initiation of POIT, and the safety of POIT, using a standardized protocol for all patients.