Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats.
Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids
Typical omega 3 polyunsaturated fatty acids (n-3 PUFAs) are docosahexaenoic acid and eicosapentaenoic acid in the form of fish oils and alpha linolenic acid from flaxseed oil. Epidemiological studies suggested the benefits of n-3 PUFA on cardiovascular health. Intervention studies confirmed that the consumption of n-3 PUFA provided benefits for primary and secondary prevention of […]
Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2; Osterix and IGF-I
Previous studies have demonstrated that dried plums which contain high amounts of polyphenols can restore bone mass and structure; and significantly increase indices of bone formation. The purpose of this study was to determine how dried plum polyphenols influence osteoblast activity and mineralized nodule formation under normal and inflammatory conditions. MC3T3-E1 cells were plated and […]
Effect of almond skin polyphenolics and quercetin on human LDL and apolipoprotein B-100 oxidation and conformation
Almond skin polyphenolics (ASP) and vitamin C (VC) or E (VE) inhibit the Cu(2+)-induced generation of conjugated dienes in human low-density lipoprotein (LDL) in a synergistic manner. However; the mechanism(s) by which this synergy occurs is unknown. As modification of apolipoprotein (apo) B-100 is an early; critical step in LDL oxidation; we examined the effects […]