INC-Funded Research
Strengthening the scientific evidence supporting the health benefits of nuts and dried fruits.
Health Research Supported by the INC
To strengthen scientific recognition of the health benefits of nuts and dried fruit and promote increased global consumption, the INC has invested over millions in dedicated initiatives.
Research Funded Since 2013
Backed by an investment of over €2 million, the INC has launched a scientific roadmap to advance a health claim for nuts, driven by two flagship initiatives: the NUTPOOL Project and the PreNut Clinical Trial, marking a clear pathway from scientific evidence to global recognition:
Retraction of the study by Gunathilake M. et al.
Prof. Jordi Salas-Salvadó
Associations between nut intake, cognitive function and nonalcoholic fatty liver disease in older adults
Dr. Sze-Yen Tan
Effects of long-term mixed nut consumption on brain health in elderly: Focus on underlying mechanisms
Prof. Ronald Mensink
Gut health: physiological, microbiological and metabolomic effects of dried fruit
Prof. Kevin Whelan
Almond, dried grape and dried cranberry and exercise performance in athletes
Prof. Jonathan Buckley
Tree nuts on cognitive function, metabolomics and intestinal microbiota
Dr. Crystal Haskell-Ramsay
Nut-based food-products on cell membranes in obese children
Dr. Sara Arranz
Nut-derived miRNAs on inflammatory and metabolic profile of fat cells
Dr. Daniele Lettieri-Barbato
Nut consumption on markers of inflammation and endothelial function
Prof. Linda Tapsell
Dried fruit and glycemic response to high glycemic index-carbohydrate foods
Dr. Cyril Kendall
Dried plums, figs, dates, and raisins on cardiometabolic disease risk factors
Dr. Penny Kris-Etherton
Nut consumption on semen quality and functionality in healthy males
Dr. Mònica Bulló
Nut consumption and weight and body fat distribution in adults
Dr. Joan Sabaté
Nuts and cognitive decline in older adults: the InCHIANTI study
Prof. Cristina Andrés Lacueva
Energy-restricted Med diet on mortality and cardiovascular disease
Dr. Miguel A. Martínez-González
Nut consumption and cognitive function with aging
Dr. Francince Grodstein
A Roapmap to a Health Claim for Nuts
Nuts are widely recognized as nutritious foods, with a growing body of research linking regular consumption to positive health outcomes. However, there is currently no category-wide health claim for nuts. For the INC, this represents an important opportunity to strengthen the scientific evidence base and support greater recognition of nuts within dietary guidance and public health policy.
Building the Evidence: NUTPOOL
Launched in 2024 and running through July 2027, NUTPOOL is a global meta-analysis bringing together data from more than one million participants worldwide. The project aims to consolidate existing evidence on nut consumption and health, creating a stronger scientific foundation for future health claim applications.
Generating New Clinical Proof: PRENUT
The PRENUT Clinical Trial is scheduled to begin in January 2027. This five-year, multi-centre study across the USA, India, Spain, and Canada will evaluate the impact of daily mixed nut consumption in individuals at risk of developing type 2 diabetes.
By generating new clinical evidence, PRENUT aims to strengthen understanding of how nuts may contribute to healthy dietary patterns and support long-term health outcomes.
From Research to Recognition
Together, NUTPOOL and PRENUT form part of the INC’s long-term roadmap to consolidate global evidence, generate new clinical research, and support future opportunities for health claims, dietary guidelines, and wider recognition of the health benefits of nuts.
>1 million participants
4 continents
3 years
NUTPOOL
is exploring the relationship between nut consumption and prevention of:
- TYPE 2 DIABETES
- CARDIOVASCULAR DISEASE
- CORONARY HEART DISEASE
- STROKE
- CANCER
- DEMENTIA
- ALZHEIMER’S DISEASE
- MORTALITY
TYPE 2 DIABETES
CARDIOVASCULAR DISEASE
CORONARY HEART DISEASE
STROKE
CANCER
DEMENTIA
ALZHEIMER’S DISEASE
MORTALITY
See previous projects that received funding
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Research grants
Promotion and disemination project grants
Global Health Claim on Nuts
The INC is taking a major step toward gaining a global health claim for nuts with the NUTPOOL Study. This groundbreaking research will collect data from 1 million participants and be the first of its kind to use a meta-analysis of various large-scale studies globally, to comprehensively investigate the association between nut consumption, chronic diseases and mortality.
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Funded Projects on Nuts & Dried Fruits
Through strategic funding, significant investments have been directed toward research that highlights the benefits of nuts and dried fruits. Grants have also been awarded to support promotional and educational initiatives, while nutrition symposia in multiple countries have helped raise awareness and share knowledge with experts and consumers worldwide.
Nut consumption and cognitive function with aging
Dr. Francince Grodstein
Energy-restricted Med diet on mortality and cardiovascular disease
Dr. Miguel A. Martínez-González
Nuts and cognitive decline in older adults: the InCHIANTI study
Prof. Cristina Andrés Lacueva
Nut consumption and weight and body fat distribution in adults
Dr. Joan Sabaté
Nut consumption on semen quality and functionality in healthy males
Dr. Mònica Bulló
Dried plums, figs, dates, and raisins on cardiometabolic disease risk factors
Dr. Penny Kris-Etherton
Dried fruit and glycemic response to high glycemic index-carbohydrate foods
Dr. Cyril Kendall
Nut consumption on markers of inflammation and endothelial function
Prof. Linda Tapsell