Almonds lower blood cholesterol and LDL-cholesterol but not HDL-cholesterol or triglycerides in human subjects: results of a meta-analysis.
Identification and quantification of flavonol glycosides in almond seedcoats using MALDI-TOF MS.
Interest in the molecular composition of almonds is growing; due to their popularity in a wide variety of food formulations. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a powerful new technique that can be used to rapidly identify and quantify possible bioactive compounds in these popular tree nuts. Four flavonol glycosides were identified […]
Variation in the flavonol glycoside composition of almond seedcoats as determined by MALDI-TOF Mass Spectrometry.
Seedcoats of 16 almond varieties were screened for flavonol glycosides by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Flavonol glycosides were extracted by a simple methanolic extraction followed by a quick cleanup procedure with a Sep-Pak C(18) cartridge. Each of the 16 seedcoat samples exhibited a unique composition. Four flavonol glycosides; isorhamnetin rutinoside; […]
Anatomy and cell wall poly-saccharides of almond (Prunus dulcis D.A. Webb) seeds.
The anatomy of Prunus dulcis was analyzed by applying several differential staining techniques and light microscopy. Prunus dulcis seed has a thin and structurally complex seed coat; with lignified cellulosic tissue. The embryo has two voluminous cotyledons. Cotyledon cells have a high number of protein and lipid bodies; some of which have phytin. The provascular […]
Role of cell walls in the bioaccessibility of lipids in almond seeds.
BACKGROUND: Certain nutrients and phytochemicals in almonds may confer protection against cardiovascular disease; but little is known about factors that influence their bioavailability. A crucial and relevant aspect is the amount of these dietary components available for absorption in the intestine; which is a concept referred to as bioaccessibility. OBJECTIVE: We investigated the role played […]
Effect of chronic consumption of almonds on body weight in healthy humans
Whole almonds activate gastrointestinal (GI) tract anti-proliferative signaling in APCmin (multiple intestinal neoplasia) mice.
Whole almonds and almond fractions reduce aberrant crypt foci in a rat model of colon carcinogenesis.
Almonds and other nuts appear to confer health benefits despite their high fat content. To assess the effect of almonds on colon cancer; whole almond-; almond meal- or almond oil-containing diet effects on aberrant crypt foci (ACF) in azoxymethane-treated F344 male rats were investigated. Six-week-old male F344 rats were fed the various almond and control […]
Effect of almond skin polyphenolics and quercetin on human LDL and apolipoprotein B-100 oxidation and conformation
Almond skin polyphenolics (ASP) and vitamin C (VC) or E (VE) inhibit the Cu(2+)-induced generation of conjugated dienes in human low-density lipoprotein (LDL) in a synergistic manner. However; the mechanism(s) by which this synergy occurs is unknown. As modification of apolipoprotein (apo) B-100 is an early; critical step in LDL oxidation; we examined the effects […]
Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol in USA
Sixteen normolipidemic male volunteers aged 41 +/- 9 y (mean +/- SD) consumed a diet providing 36% of energy as fat (92 g fat/d) for 9 wk. A daily supplement of nuts (providing half of the total fat intake) was provided against a common background diet. In the first 3-wk period the background diet was […]