Whole almonds activate gastrointestinal (GI) tract anti-proliferative signaling in APCmin (multiple intestinal neoplasia) mice.

Whole almonds and almond fractions reduce aberrant crypt foci in a rat model of colon carcinogenesis.

Almonds and other nuts appear to confer health benefits despite their high fat content. To assess the effect of almonds on colon cancer; whole almond-; almond meal- or almond oil-containing diet effects on aberrant crypt foci (ACF) in azoxymethane-treated F344 male rats were investigated. Six-week-old male F344 rats were fed the various almond and control […]

Effect of almond skin polyphenolics and quercetin on human LDL and apolipoprotein B-100 oxidation and conformation

Almond skin polyphenolics (ASP) and vitamin C (VC) or E (VE) inhibit the Cu(2+)-induced generation of conjugated dienes in human low-density lipoprotein (LDL) in a synergistic manner. However; the mechanism(s) by which this synergy occurs is unknown. As modification of apolipoprotein (apo) B-100 is an early; critical step in LDL oxidation; we examined the effects […]

Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol in USA

Sixteen normolipidemic male volunteers aged 41 +/- 9 y (mean +/- SD) consumed a diet providing 36% of energy as fat (92 g fat/d) for 9 wk. A daily supplement of nuts (providing half of the total fat intake) was provided against a common background diet. In the first 3-wk period the background diet was […]

Purification; identification and preliminary crystallographic studies of Pru du amandin; an allergenic protein from Prunus dulcis

Food allergies appear to be one of the foremost causes of hypersensitivity reactions. Nut allergies account for most food allergies and are often permanent. The 360 kDa hexameric protein Pru du amandin; a known allergen; was purified from almonds (Prunus dulcis) by ammonium sulfate fractionation and ion-exchange chromatography. The protein was identified by a BLAST […]