Antioxidant; larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents

Anacardic acid; cardanol and cardol; the main constituents of natural cashew nut shell liquid (CNSL); were obtained by solvent extraction and assayed for antioxidant; larvicidal and antiacetylcholinesterase activity. Their relative percent composition was obtained by HPLC analysis. Antioxidant activity was assessed using the DPPH and ABTS(+) tests; which showed cardanol as the most active; followed […]

Study on antioxidant activity of common dry fruits

This study investigates the antioxidant activity of different dry fruits (almonds; walnut; cashew nut; raisins and chironji) through several chemical and biochemical assays: reducing power; lipid peroxidation damage in biomembranes and determination of antioxidant enzymes activity (SOD and CAT). To estimate the total phenolic content; the assay using Folin-Ciocalteu reagent was used. The EC(50) values […]

Hydro-ethanolic extract of cashew tree (Anacardium occidentale) nut and its principal compound; anacardic acid; stimulate glucose uptake in C2C12 muscle cells

Scope: Products of cashew tree (Anacardium occidentale) are used in traditional medicine for various ailments; including diabetes.Methods and results: The anti-diabetic properties of cashew plant parts were studied using differentiated C2C12 myoblasts (myotubes) and rat liver mitochondria. Hydroethanolic extract of cashew seed (CSE) and its active component; anacardic acid (AA); stimulated glucose transport into C2C12 […]

Protective effect of anacardic acids from cashew (Anacardium occidentale) on ethanol-induced gastric damage in mice

Cashew nut-shell liquid and the contained anacardic acids (AAs) have been shown to possess antioxidant; lipoxygenase inhibitory; anti-Helicobacter pylori and antitumor properties. Despite these known effects; hitherto there were no published reports on their likely gastroprotective effects. The present study was designed to verify whether AAs afford gastroprotection against the ethanol-induced gastric damage and to […]

The anti-ophidian properties of Anacardium occidentale bark extract

Snakebites in rural areas of tropical and subtropical regions are commonly treated with medicinal plants. In this report; we have studied the ability of Anacardium occidentale bark extract to neutralize enzymatic as well as pharmacological effects induced by Vipera russelii venom. The extract neutralized the viper venom hydrolytic enzymes such as phospholipase; protease; and hyaluronidase […]

New potential AChE inhibitor candidates

We have theoretically studied new potential candidates of acetylcholinesterase (AChE) inhibitors designed from cardanol; a non-isoprenoid phenolic lipid of cashew Anacardium occidentale nut-shell liquid. The electronic structure calculations of fifteen molecule derivatives from cardanol were performed using B3LYP level with 6-31G; 6-31G(d); and 6-311+G(2d;p) basis functions. For this study we used the following groups: methyl; […]