Early Peanut Introduction in Infants: Improving Guideline Adherence With EMR Standardization
Objectives: Peanut allergy in children is a population health problem. Evidence suggests early peanut introduction (EPI) for infants can reduce the development of peanut allergy. Primary care settings have not widely adopted guidelines recommending EPI. Peanut allergy prevention depends on primary care providers incorporating EPI guidelines into well-child check (WCC) encounters. We aimed to improve […]
Fast impedimetric immunosensing of IgGs associated with peanut and hazelnut allergens
Food allergies trigger a variety of clinical adverse symptoms and clinical evidence suggests that the presence of food allergy-related IgG can be helpful in the diagnosis when analyzed at the peptide-epitope level. To validate and select the peptides based on their specificity toward hazelnut or peanut epitopes, the authors of this study developed a silicon-based […]
EAACI guidelines on the diagnosis of IgE-mediated food allergy
This European Academy of Allergy and Clinical Immunology guideline provides recommendations for diagnosing IgE-mediated food allergy and was developed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Food allergy diagnosis starts with an allergy-focused clinical history followed by tests to determine IgE sensitization, such as serum allergen-specific IgE (sIgE) and skin prick […]
Revised Swedish infant feeding guidelines are associated with earlier introduction of allergenic foods.
Background: Randomized controlled trials have demonstrated that early introduction of allergenic foods, such as peanut and egg, can reduce food allergy in high-risk children. Many international guidelines recommend introduction in the first year of life and accordingly, the Swedish National Food agency released updated guidelines in June 2019. Objective: To examine if the age at […]
Aflatoxins and Ochratoxin A in dried fruits from Morocco: Monitoring, regulatory aspects, and exposure assessment.
The present study aims to investigate the presence of Aflatoxins (AF) in 180 samples dried fruits and Ochratoxin A (OTA) in 210 samples dried fruits and grape juices collected in Morocco. Mycotoxins were analyzed by high performance liquid chromatography (HPLC) coupled to fluorescence detection and immunoaffinity columns (IAC) cleanup. Contamination levels were compared with the […]
Safety and effectiveness of peanut oral immunotherapy in children under 12 months
Peanut oral immunotherapy is an option for the treatment of peanut allergy. Our study suggests that peanut oral immunotherapy in children aged less than 12 months is safe and effective. https://doi.org/10.1016/j.jaip.2023.07.009
Consumption of peanut products enhances the production of microbial phenolic metabolites related with memory and stress response: Results from the ARISTOTLE trial
Based on evidence demonstrating that gut microbiota can metabolize dietary polyphenols to more readily absorbable phenolic acids, this study aimed to evaluate the association of urinary microbial phenolic metabolites (MPMs) related to peanut intake with memory function and stress response. A total of 63 healthy young adults from a randomized controlled trial completed the intervention, […]
The relevance of oral food challenge in a patient allergic to peanut and tree nuts
Peanut allergy is one of the most common food allergies in childhood. In vitro cross-sensitization between peanut and tree nuts (TN) is high, but only a subgroup of patients allergic to peanut will have a concomitant allergy to one or several TN. In this article, the authors report a case of a 12-year-old boy who […]
Longitudinal dynamics of the gut microbiome and metabolome in peanut allergy development
Background: Rising rates of peanut allergy motivate investigations of its development to inform prevention and therapy. Microbiota and the metabolites they produce shape food allergy risk. Objective: To gain insight into gut microbiome and metabolome dynamics in the development of peanut allergy. Methods: We performed a longitudinal, integrative study of the gut microbiome and metabolome […]
Effect of Peanut Paste-based Ready-to-use School Meals With and Without Milk on Fluid Cognition in Northern Ghana: A Randomized Controlled Trial
Background: Few studies have investigated the role of school feeding in low- and middle-income countries as a means of improving childhood cognition. Peanut/milk ready-to-use food (PM-RUF) or cowpea offers an affordable, scalable option that might improve cognition. Objectives: To determine whether micronutrient-fortified PM-RUF or peanut/cowpea ready-to-use food (PC-RUF) would improve fluid cognition as assessed by […]