Multi-dimensional study of the oral microbiome, metabolite, and immunologic environment in peanut allergy

Background: The oral mucosa is the initial interface between food antigens, microbiota and mucosal immunity, yet little is known about oral host-environment dynamics in food allergy. Objective: To determine oral microbial, metabolic, and immunologic profiles associated with peanut allergy. Methods: We recruited 105 subjects (peanut allergic n=56, healthy subjects n=49) for salivary microbiome profiling using […]

Emerging developments in the forefront of peanut oral immunotherapy

Purpose of review: Despite the COVID-19 pandemic, progress continued in the field of peanut oral immunotherapy over the past 12 to 18 months. Of importance, the first oral immunotherapy product for the treatment of peanut allergy was approved by the US Food and Drug Administration in January 2020. Recent findings: Suggested modifications to the practice […]

Resveratrol promotes liver regeneration in drug-induced liver disease in mice

Studies suggest that the bioactive polyphenolic compound resveratrol (RESV, trans-isomer), found naturally in certain foods such as red grapes and peanuts, may be able to ameliorate liver damage. However, the effects and efficacy of long-term treatment with RESV remain unclear. Here, we used an acetaminophen (APAP; 400 mg/kg/d for 15 days) overdose model to induce […]

Optimization of deficit irrigation and nitrogen fertilizer management for peanut production in an arid region

Deficit irrigation (DI) has been emerging as an important technique for enhancing crop water productivity (WP). However, advantage of DI under varying nitrogen (N) application rates remains unclear. Field experiments were conducted during 2012-2014 to investigate the impacts of six irrigation levels[FI (full irrigation), DI10, DI20, DI30, DI40 and DI50, with irrigation amount of 100, […]

Peanut disease epidemiology under dynamic microclimate conditions and management practices in North Florida

Diverse field characteristics, weather patterns, and management practices can result in variable microclimates. The objective was to relate in-field microclimate conditions with peanut diseases and yield and determine the effect of irrigation and fungicides within these environments. Irrigation did not have a major impact on disease and yield. Stem rot (Athelia rolfsii) and early (Passalora […]