Pistachios increase serum antioxidants and lower serum oxidized-LDL in hypercholesterolemic adults

Pistachios are high in lutein; beta-carotene; and gamma-tocopherol relative to other nuts; however; studies of the effects of pistachios on oxidative status are lacking. We conducted a randomized; crossover controlled-feeding study to evaluate 2 doses of pistachios on serum antioxidants and biomarkers of oxidative status in 28 hypercholesterolemic adults (LDL-cholesterol >or=2.86 mmol/L). Participants consumed 3 […]

Pistachios Increase Serum Antioxidants and Lower Serum Oxidized-LDL in Hypercholesterolemic Adults

Pistachios are high in lutein; beta-carotene; and gamma-tocopherol relative to other nuts; however; studies of the effects of pistachios on oxidative status are lacking. We conducted a randomized; crossover controlled-feeding study to evaluate 2 doses of pistachios on serum antioxidants and biomarkers of oxidative status in 28 hypercholesterolemic adults (LDL-cholesterol >/=2.86 mmol/L). Participants consumed 3 […]

Effect of pistachio oil on gene expression of IFN-induced protein with tetratricopeptide repeats 2: A biomarker of inflammatory response

When incorporated into the diet; pistachios have a beneficial effect on lipid and lipoprotein profiles. However; little is known about potential anti-inflammatory properties. This study was conducted to determine whether pistachio oil and an organic extract from pistachio oil extract (PE) regulated expression of inflammation-related genes. A mouse macrophage cell line (RAW 264.7 cells) was […]

Effect of pistachio diet on lipid parameters; endothelial function; inflammation; and oxidative status: A prospective study

OBJECTIVE: Recent studies have suggested that nuts have favorable effects beyond lipid lowering. We aimed to investigate effect of the Antep pistachio (Pistacia vera L.) on blood glucose; lipid parameters; endothelial function; inflammation; and oxidation in healthy young men living in a controlled environment. METHODS: A Mediterranean diet was administered to normolipidemic 32 healthy young […]

Identification of two pistachio allergens; Pis v 1 and Pis v 2; belonging to the 2S albumin and 11S globulin family

BACKGROUND: IgE-mediated allergic reactions to pistachio appear to be occurring more frequently; however; little is known about its allergenic proteins. OBJECTIVE: We attempted to identify pistachio allergens and to clone the encoding genes. METHODS: Pistachio proteins were extracted and separated by SDS-PAGE. Immunolabelling was performed with sera from 28 pistachio-allergic individuals. Proteins of interest were […]

Consumption of pistachio nuts beneficially affected blood lipids and total antioxidant activity in rats fed a high-cholesterol diet

Although nuts are typically high in dietary fat; novel studies have shown that regular consumption of these heart-healthy foods might confer a beneficial effect on cardiovascular disease risk. In the present study; we aimed to analyse the effects of pistachio consumption on blood lipids; antioxidant activity; oxidative stress and sialic acid levels in high-fat-fed rats […]

The lipid messenger OEA links dietary fat intake to satiety

The association between fat consumption and obesity underscores the need to identify physiological signals that control fat intake. Previous studies have shown that feeding stimulates small-intestinal mucosal cells to produce the lipid messenger oleoylethanolamide (OEA) which; when administered as a drug; decreases meal frequency by engaging peroxisome proliferator-activated receptors-alpha (PPAR-alpha). Here; we report that duodenal […]