Characterization and Antioxidative Properties of Oligomeric Proanthocyanidin from Prunes; Dried Fruit of Prunus domestica L
A prune extract was separated by an antioxidant-guided assay to obtain an oligomeric proanthocyanidin fraction. The antioxidative oligomer was characterized as a procyanidin oligomer with an average polymerization degree of five and composed of epicatechin and catechin units. The antioxidative activity of the oligomer showed greater potency than chlorogenic acid which is known as an […]
Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia.
Forty-one free-living adult men with mild hypercholesterolemia (5.2-7.5 mmol/L) voluntarily participated in an 8-wk crossover study designed to determine the effect of prunes as a source of fiber on plasma cholesterol and on fecal output and bile acid concentration. During the prune period, subjects supplemented their usual diets with 12 prunes (100 g; 6 g dietary fiber) daily. Plasma low-density-lipoprotein cholesterol was significantly lower after the prune period (3.9 mmol/L) […]
Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway
Previously; dietary supplementation with dried plums; a rich source of polyphenolic compounds with antioxidant and anti-inflammatory properties; has been shown to improve bone density; microstructure and biomechanics in female animal models of osteopenia. We designed this study to determine the extent to which dried plum prevents skeletal deterioration in gonadal hormone deficient male animals and […]
Phenolic composition and antioxidant activity of prunes and prune juice (Prunus domestica).
Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats
SUMMARY: Bone loss was confirmed after 90 days in 50 6-month-old male Sprague Dawley rats that were sham-operated or orchidectomized (ORX). In this study; we have shown that dried plum (DP) has potent effects on bone in terms of bone mass; microarchitecture; and strength in osteopenic male rats. Although these changes may be mediated through […]