Evaluation of the Introduction of Allergen Containing Foods: Feeding Infants and Toddlers Study (FITS) 2016

Background: Guidelines on early introduction of allergen-containing foods are evolving; however, little national data exist defining current allergen feeding practices. Objective: To investigate consumption rates of foods containing egg and peanut among infants and toddlers prior to guideline changes in 2017. Methods: The Feeding Infants and Toddlers Study (FITS) 2016 was conducted nationally among 3235 caregivers with a […]

Recent advances in the management of nut allergy

Peanut/tree nut allergy is common and has been associated with particularly severe reactions. Epidemiological data have shown that the prevalence ranges between 0.05% and 4.9% for tree nut and between 0.5% and 3% for peanut. These large variations can be explained by differences in the age of included patients and the geographical region. In addition, […]

Age and eczema severity, but not family history, are major risk factors for peanut allergy in infancy.

Background: Whether to screen high-risk groups before early peanut introduction is controversial. Objective: We sought to determine the risk of peanut allergy (PA) before peanut introduction for infants with (1) moderate-severe eczema, (2) another food allergy (FA), and/or (3) a first-degree relative with peanut allergy (FH). Methods: Infants aged 4 to 11 months with no history of peanut […]

Journal of Allergy and Clinical Immunology. Allergy / peanuts Ara h 2–specific IgE is superior to whole peanut extract–based serology o

Background: Screening of high-risk infants for peanut allergy (PA) before introduction is now recommended in the United States, but the optimal approach is not clear. Objective: We sought to compare the diagnostic test characteristics of peanut skin prick test (SPT), peanut-specific IgE (sIgE), and sIgE to peanut components in a screening population of infants before known peanut […]

Prevalence of Self-Reported Food Allergies and Their Association with Other Health Conditions among Adults in Saudi Arabia.

Food allergies are a potentially life-threatening health issue, and few studies have determined their prevalence throughout Saudi Arabia. The main objective of our study was to estimate the prevalence and distribution of self-reported food allergies, and explore their association with other health conditions among adults in Saudi Arabia. This study was a nationwide cross-sectional survey […]

Mechanisms of oral immunotherapy.

Food allergy presents a significant global health concern with up to 10% of the population affected in developed nations and a steadily increasing prevalence. In many cases, particularly with peanut, tree nut and shellfish, food allergy is a lifelong and potentially life-threatening diagnosis. While no 'cure' for IgE-mediated food allergy exists, oral immunotherapy (OIT) is […]

Hazelnut Allergy.

Background and Objectives: Hazelnuts are frequently involved in IgE-mediated reactions and represent the main culprit of nut allergy in Europe. The clinical presentation varies from mild symptoms limited to the oropharynx [oral allergy syndrome (OAS)], due to the cross-reaction with homologues in pollen allergens and more severe events caused by the primary sensitization to highly stable […]

Epitope mapping of the major allergen 2S albumin from pine nut.

The epitopes of the major allergen of pine nut, Pin p 1, were analyzed using a peptide library and sera from patients with clinical allergy to pine nut in order to deepen into the allergenic characteristics of Pin p 1. Analyses of epitope similarities and epitopes location in a 3D-model were also performed. Results showed […]

The accuracy of diagnostic testing in determining tree nut allergy: a systematic review.

Background: Food allergy is most accurately diagnosed by a formal oral food challenge however it is time and labor intensive, risks the individual to severe reaction and access is often a limiting step in the diagnostic process. This is compounded for tree nut allergy diagnosis as several oral food challenges may be required to determine allergy […]