Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular […]

Effects of different forms of hazelnuts on blood lipids and a-tocopherol concentrations in mildly hypercholesterolemic individuals.

Background/Objectives: Diets high in nuts reduce cholesterol; probably due to their favorable lipid profile and other bioactive substances. However; the physical form of the nut may be important as the cell wall of intact nuts may limit the hypocholesterolemic effect of nuts by reducing lipid bioavailability. Therefore; we investigated the effects on blood lipids of […]