The evidence for dietary prevention and treatment of cardiovascular disease.
During the past few decades numerous studies have reported the atherogenic potential of saturated fatty acids; trans-fatty acids; and cholesterol; and beneficial effects of fiber; phytostanols/phytosterols; n-3 fatty acids; a Mediterranean diet; and other plant-based approaches. The purpose of this article is to provide a comprehensive and systematic review of the evidence associated with key […]
The Nutrition Facts label on a bag of almonds lists 1 gram of saturated fat per serving. Is this the same type of saturated fat that's in a hamburger?
Vitamin E Consumption and the risk of coronary heart disease in women.
BACKGROUND. Interest in the antioxidant vitamin E as a possible protective nutrient against coronary disease has intensified with the recognition that oxidized low-density lipoprotein may be involved in atherogenesis. METHODS. In 1980; 87;245 female nurses 34 to 59 years of age who were free of diagnosed cardiovascular disease and cancer completed dietary questionnaires that assessed […]
The DASH diet; sodium intake and blood pressure trial (DASH-sodium): rationale and design
The DASH Diet; Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter; randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with stage 1 hypertension (120-159/80-95 mm Hg). The 2 dietary patterns are a control diet […]
Including walnuts in a low fat/modified fat diet improves hdl cholesterol-to-total cholesterol ratios in patients with type 2 diabetes
OBJECTIVE: The aim of this study was to examine the effect of a moderate-fat diet inclusive of walnuts on blood lipid profiles in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a parallel randomized controlled trial comparing three dietary advice groups each with 30% energy as fat: low fat; modified low fat; […]
Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia.
Forty-one free-living adult men with mild hypercholesterolemia (5.2-7.5 mmol/L) voluntarily participated in an 8-wk crossover study designed to determine the effect of prunes as a source of fiber on plasma cholesterol and on fecal output and bile acid concentration. During the prune period, subjects supplemented their usual diets with 12 prunes (100 g; 6 g dietary fiber) daily. Plasma low-density-lipoprotein cholesterol was significantly lower after the prune period (3.9 mmol/L) […]
Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high-risk patients (Indo-Mediterranean Diet Heart Study): a randomized single-blind trial.
BACKGROUND: The rapid emergence of coronary artery disease (CAD) in south Asian people is not explained by conventional risk factors. In view of cardioprotective effects of a Mediterranean style diet rich in alpha-linolenic acid; we assessed the benefits of this diet for patients at high risk of CAD. METHODS: We did a randomised; single-blind trial […]
An Indian experiment with nutritional modulation in acute myocardial infarction
In a randomized; single-blind intervention trial; 406 patients 24 to 48 hours after acute myocardial infarction (AMI) were assigned to either diet A (204 patients; group A) or B (202 patients; group B) for 6 weeks. At entry to the study; mean age; male sex; risk factors; complications; possible and definite AMI; and drug therapy […]
Nuts and plasma lipids: an almond-based diet lowers LDL-C while preserving HDL-C.
OBJECTIVE: To compare lipid-altering effects of an almond-based diet with an olive oil-based diet; against a cheese and butter-based control diet. METHODS: Forty-five free-living hyperlipidemic men (n = 12) and women (n = 33) with a mean plasma total cholesterol (TC) of 251 +/- 30 mg/dL followed one of three diets; almond-based; olive oil-based; or […]
Effect of a diet high in monounsaturated fat from almonds on plasma cholesterol and lipoproteins.
The effect of almonds as part of a low saturated fat; low cholesterol; high-fiber diet was studied in 26 adults (13 men; 13 women). The baseline diet was modified in a similar way for all subjects by limiting meat; fatty fish; high-fat milk products; eggs; and saturated fat. Grains; beans; vegetables; fruit; and low-fat milk […]