The evidence for dietary prevention and treatment of cardiovascular disease.
During the past few decades numerous studies have reported the atherogenic potential of saturated fatty acids; trans-fatty acids; and cholesterol; and beneficial effects of fiber; phytostanols/phytosterols; n-3 fatty acids; a Mediterranean diet; and other plant-based approaches. The purpose of this article is to provide a comprehensive and systematic review of the evidence associated with key […]
The Nutrition Facts label on a bag of almonds lists 1 gram of saturated fat per serving. Is this the same type of saturated fat that's in a hamburger?
Vitamin E Consumption and the risk of coronary heart disease in women.
BACKGROUND. Interest in the antioxidant vitamin E as a possible protective nutrient against coronary disease has intensified with the recognition that oxidized low-density lipoprotein may be involved in atherogenesis. METHODS. In 1980; 87;245 female nurses 34 to 59 years of age who were free of diagnosed cardiovascular disease and cancer completed dietary questionnaires that assessed […]
The DASH diet; sodium intake and blood pressure trial (DASH-sodium): rationale and design
The DASH Diet; Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter; randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with stage 1 hypertension (120-159/80-95 mm Hg). The 2 dietary patterns are a control diet […]
Including walnuts in a low fat/modified fat diet improves hdl cholesterol-to-total cholesterol ratios in patients with type 2 diabetes
OBJECTIVE: The aim of this study was to examine the effect of a moderate-fat diet inclusive of walnuts on blood lipid profiles in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a parallel randomized controlled trial comparing three dietary advice groups each with 30% energy as fat: low fat; modified low fat; […]
Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia.
Forty-one free-living adult men with mild hypercholesterolemia (5.2-7.5 mmol/L) voluntarily participated in an 8-wk crossover study designed to determine the effect of prunes as a source of fiber on plasma cholesterol and on fecal output and bile acid concentration. During the prune period, subjects supplemented their usual diets with 12 prunes (100 g; 6 g dietary fiber) daily. Plasma low-density-lipoprotein cholesterol was significantly lower after the prune period (3.9 mmol/L) […]
Pistachio nuts and serum lipid levels in patients with moderate hypercholesterolemia. 2003; Submitted to AJCN.
Objective: Clinical and epidemiological studies have reported the beneficial effects of tree nuts and peanuts on serum lipid levels. We studied the effects of consuming 15% of the daily caloric intake in the form of pistachio nuts on the lipid profiles of free-living human subjects with primary; moderate hypercholesterolemia (serum cholesterol greater than 210 mg/dL). […]
Pistachio nut consumption and serum lipid levels.
OBJECTIVE: Clinical and epidemiological studies have reported the beneficial effects of tree nuts and peanuts on serum lipid levels. We studied the effects of consuming 15% of the daily caloric intake in the form of pistachio nuts on the lipid profiles of free-living human subjects with primary; moderate hypercholesterolemia (serum cholesterol greater than 210 mg/dL). […]
Serum fatty acids and the risk of stroke
BACKGROUND AND PURPOSE: To examine the relationship between serum fatty acids; which reflect dietary intake; and stroke; we conducted a nested case-control study of 96 men with incident stroke and 96 control subjects matched by age; clinical center; treatment group; and date of randomization who were enrolled in the Multiple Risk Factor Intervention Trial. METHODS: […]
Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high-risk patients (Indo-Mediterranean Diet Heart Study): a randomized single-blind trial.
BACKGROUND: The rapid emergence of coronary artery disease (CAD) in south Asian people is not explained by conventional risk factors. In view of cardioprotective effects of a Mediterranean style diet rich in alpha-linolenic acid; we assessed the benefits of this diet for patients at high risk of CAD. METHODS: We did a randomised; single-blind trial […]