Diet and coronary heart disease: beyond dietary fats and low-density-lipoprotein cholesterol.
Traditionally; the effects of diet on coronary heart disease have been attributed to the effects of medium-chain fatty acids; soluble fiber; and dietary cholesterol on serum low-density-lipoprotein (LDL) cholesterol concentrations. We review evidence here that many other dietary substances may affect risk; often via mechanisms not involving LDL-cholesterol concentrations directly. Such substances include phytosterols; tocotrienols; […]
Nut consumption; lipids and risk of a coronary event.
In the past; many have avoided nuts because of their high fat content. The Dietary Approaches to Stop Hypertension (DASH) diet; however; recommends regular consumption of this food along with seeds and dried beans (4-5 servings per week) as part of a diet to control hypertension. Nuts are nutrient-dense and most of their fat is […]
Effect of risk factor values on lifetime risk of and age at first coronary event.
The effect of traditional coronary heart disease risk factors on lifetime risk; age at onset; and survival free of coronary disease has not been extensively studied. The authors have used the cohort data from 27;321 California Seventh-day Adventists who had no known heart disease in 1976 to investigate these questions. Multiple decrement life tables incorporating […]
A Possible effect of nut consumption on risk of coronary heart disease;
BACKGROUND: Although dietary factors are suspected to be important determinants of coronary heart disease (CHD) risk; the direct evidence is relatively sparse. METHODS: The Adventist Health Study is a prospective cohort investigation of 31;208 non-Hispanic white California Seventh-Day Adventists. Extensive dietary information was obtained at baseline; along with the values of traditional coronary risk factors. […]
Risk factors for all-cause and coronary heart disease mortality in the oldest-old.
BACKGROUND: The oldest-old population (> or = 84 years of age) is growing rapidly and consumes a disproportionate amount of health care dollars. Risk factors for disease have not been extensively studied in this group. METHODS: A cohort study of non-Hispanic white Seventh-Day Adventists from California allowed follow-up for mortality from 1976 through 1988. Associations […]
Almonds lower blood cholesterol and LDL-cholesterol but not HDL-cholesterol or triglycerides in human subjects: results of a meta-analysis.
The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease in USA.
The author and four independent experts evaluated the intent and quality of scientific evidence for a potential beneficial health relationship between the intake of walnuts and the reduction and prevention of coronary heart disease. The report also addresses the supporting evidence for the health benefit of other tree nuts and selected legumes. Compared to most […]
Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium.
BACKGROUND: Resveratrol is a phytoalexin present in red wine. It has been shown to protect LDL from peroxidative degradation. OBJECTIVE: In consideration of the low plasma concentration of orally adsorbed resveratrol (which is insufficient for antioxidant protection of LDL); we studied another effect of the compound. DESIGN: Because resveratrol is a tyrosine kinase inhibitor like […]
Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trial.
Background: Despite the richness in antioxidants of the Mediterranean diet; to our knowledge; no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation. Methods: A total of 372 subjects at high cardiovascular risk (210 women and 162 men; age range; 55-80 years); who were recruited into a large; multicenter; randomized; controlled; parallel-group […]
Associations between diet and cancer; ischemic heart disease; and all-cause mortality in non-hispanic white California Seventh-day Adventists.
Results associating diet with chronic disease in a cohort of 34192 California Seventh-day Adventists are summarized. Most Seventh-day Adventists do not smoke cigarettes or drink alcohol; and there is a wide range of dietary exposures within the population. About 50% of those studied ate meat products or =3 times/wk compared with vegetarians]; significant protective associations […]