Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson’s Disease.
Anacardic acids (AAs) are alkyl phenols mainly presenting in cashew nuts. The antioxidant effects of these compounds have been an area of interest in recent research, with findings suggesting potential therapeutic use for certain diseases. Nevertheless, none of these studies were performed in order to test the hypothesis of whether anacardic acids are capable of […]
Dietary patterns and risk of Parkinson's disease: a case-control study in Japan
Background: Nearly all epidemiologic studies examining the association between the risk of Parkinson's disease (PD) and diet have focused on single foods and specific nutrients. However; epidemiologic evidence for the association of dietary pattern with PD; namely the measurement of overall diet by considering the cumulative effects of nutrients is extremely limited. We conducted a […]
Comparative study between two animal models of extrapyramidal movement disorders: Prevention and reversion by pecan nut shell aqueous extract
Abstract: Acute reserpine and subchronic haloperidol are animal models of extrapyramidal disorders often used to study Parkinsonism; akinesia and tardive dyskinesia. In humans; these usually irreversible and disabling extrapyramidal disorders are developed by typical antipsychotic treatment; whose pathophysiology has been related to oxidative damages development. So far; there is no treatment to prevent these problems […]
Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases
Resveratrol is a phytoalexin structurally related to stilbenes; which is synthesized in considerable amounts in the skin of grapes; raspberries; mulberries; pistachios and peanuts; and by at least 72 medicinal and edible plant species in response to stress conditions. It was isolated in 1940 and did not maintain much interest for around five decades until […]
Prospective study of dietary pattern and risk of Parkinson disease.
BACKGROUND: Several studies have shown associations between Parkinson Disease (PD) risk and individual foods and nutrients with inconsistent results. OBJECTIVE: We examined associations between dietary patterns and risk of PD in the Health Professionals Follow-Up Study (1986-2002) and the Nurses' Health Study (1984-2000). DESIGN: We included 49 692 men and 81 676 women free of […]