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Products: Peanuts
Subject: Allergy

Screening of probiotic Lactobacillus to reduce peanut allergy and with potential anti-allergic activity

Authors: Yang, S., Peng, Z., Hardie, W. J., Huang, T., Tang, H., Liu, Z., Liu, Q., Xiao, M., Xiong, T., & Xie, M.
  • Journals: J Sci Food Agric.
  • Pages:
  • Volume: 10.1002/jsfa.13089
  • Year: 2023
Background: Peanut is a significant source of nutrition and a valuable oilseed crop. It is also a serious allergy source, which poses a threat to 1.1% of the population. This study aimed to screen lactic acid bacteria (LAB) with the capacity to alleviate peanut allergenicity and exhibit anti-allergic properties. Result: The results show that LAB can make use of substances in peanuts to reduce the pH of peanut milk from 6.603 to 3.593-4.500 by acid production and that it can utilize the protein in peanuts to reduce the allergenic content (especially Ara h 1) and improve biological activity in peanut pulp. The content of Ara h 1 peanut-sensitizing protein was reduced by 74.65% after fermentation. The protein extracted from fermented peanut pulp is more readily digestible by gastrointestinal juices. The inhibitory activity assay of hyaluronidase (an enzyme with strong correlation to allergy) increased from 46.65% to a maximum of 90.57% to reveal that LAB fermentation of peanut pulp exhibited a robust anti-allergic response. Conclusion: The strains identified in this study exhibited the ability to mitigate peanut allergenicity partially and to possess potential anti-allergic properties. Lactobacillus plantarum P1 and Lactobacillus salivarius C24 were identified as the most promising strains and were selected for further research. © 2023 Society of Chemical Industry.
https://doi.org/10.1002/jsfa.13089