The lipid messenger OEA links dietary fat intake to satiety

The association between fat consumption and obesity underscores the need to identify physiological signals that control fat intake. Previous studies have shown that feeding stimulates small-intestinal mucosal cells to produce the lipid messenger oleoylethanolamide (OEA) which; when administered as a drug; decreases meal frequency by engaging peroxisome proliferator-activated receptors-alpha (PPAR-alpha). Here; we report that duodenal […]

The effect of Korean pine nut oil on in vitro CCK release; on appetite sensations and on gut hormones in post-menopausal overweight women

Appetite suppressants may be one strategy in the fight against obesity. This study evaluated whether Korean pine nut free fatty acids (FFA) and triglycerides (TG) work as an appetite suppressant. Korean pine nut FFA were evaluated in STC-1 cell culture for their ability to increase cholecystokinin (CCK-8) secretion vs. several other dietary fatty acids from […]

Nut; corn; and popcorn consumption and the incidence of diverticular disease

CONTEXT: Patients with diverticular disease are frequently advised to avoid eating nuts; corn; popcorn; and seeds to reduce the risk of complications. However; there is little evidence to support this recommendation. OBJECTIVE: To determine whether nut; corn; or popcorn consumption is associated with diverticulitis and diverticular bleeding. DESIGN AND SETTING: The Health Professionals Follow-up Study […]

Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study

BACKGROUND: Nut consumption lowers cardiovascular disease (CVD) risk. Studies are lacking about the effects of pistachios; a nutrient-dense nut; on CVD risk factors; dose-response relations; and lipid-lowering mechanisms. OBJECTIVE: We evaluated the effects of 2 doses of pistachios; added to a lower-fat diet; on lipids and lipoproteins; apolipoprotein (apo)-defined lipoprotein subclasses; and plasma fatty acids. […]

Dried plums (prunes) reduce atherosclerosis lesion area in apolipoprotein E-deficient mice

Dried plums are a fruit high in pectin with substantial antioxidant activity. Previous studies in rats and man indicate that dried plums or plum fibre lower liver and plasma cholesterol; respectively. The apoE-deficient mouse; which develops atherosclerotic lesions rapidly when fed cholesterol; was used to determine the ability of dried plums to reduce atherosclerosis. Diets […]

Adherence to Mediterranean diet and health status: meta-analysis

OBJECTIVE: To systematically review all the prospective cohort studies that have analyzed the relation between adherence to a Mediterranean diet; mortality; and incidence of chronic diseases in a primary prevention setting. DESIGN: Meta-analysis of prospective cohort studies. DATA SOURCES: English and non-English publications in PubMed; Embase; Web of Science; and the Cochrane Central Register of […]

Breakfast: a good habit; not a repetitive custom

In developed countries; obesity is the most frequent nutritional disorder; and overweight and obesity prevalences have increased whilst physical activity and breakfast consumption have declined. There is growing scientific interest in the possible role of breakfast in weight control and in factors such as appetite control; dietary quality and reduced risk for chronic diseases. The […]

In vivo and T Cell Cross-Reactivity between Walnut; Cashew and Peanut

Background: Examination of IgE cross-reactivity among nuts has been limited to in vitro experiments. Cross-reactivity studies of nuts at the T cell level are difficult to interpret because of the inability to determine which cellular responses are from a true sensitization and which are due to cross-reactivity. Using a mouse model in which the sensitizing […]

Suppression of implanted MDA-MB 231 human breast cancer growth in nude mice by dietary walnut

Walnuts contain components that may slow cancer growth including omega 3 fatty acids; phytosterols; polyphenols; carotenoids; and melatonin. A pilot study was performed to determine whether consumption of walnuts could affect growth of MDA-MB 231 human breast cancers implanted into nude mice. Tumor cells were injected into nude mice that were consuming an AIN-76A diet […]