Long-term effects of increased dietary polyunsaturated fat from walnuts on metabolic parameters in type II diabetes

Background/Objectives:Most dietary interventions have metabolic effects in the short term; but long-term effects may require dietary fat changes to influence body composition and insulin action. This study assessed the effect of sustained high polyunsaturated fatty acids (PUFA) intake through walnut consumption on metabolic outcomes in type II diabetes.Subjects/Methods:Fifty overweight adults with non-insulin-treated diabetes (mean age […]

Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition; Physical Activity; and Metabolism; Council on Cardiovascular Nursing; and Council on Epidem

A large body of literature suggests that higher intakes of omega-6 (or n-6) polyunsaturated fatty acids (PUFAs) reduce risk for coronary heart disease (CHD). However; for the reasons outlined below; some individuals and groups have recommended substantial reductions in omega-6 PUFA intake. The purpose of this advisory is to review evidence on the relationship between […]

Dried plums (prunes) reduce atherosclerosis lesion area in apolipoprotein E-deficient mice

Dried plums are a fruit high in pectin with substantial antioxidant activity. Previous studies in rats and man indicate that dried plums or plum fibre lower liver and plasma cholesterol; respectively. The apoE-deficient mouse; which develops atherosclerotic lesions rapidly when fed cholesterol; was used to determine the ability of dried plums to reduce atherosclerosis. Diets […]

Mastication of almonds: effects of lipid bioaccessibility; appetite; and hormone response

BACKGROUND: Epidemiologic and clinical data indicate that nuts can be incorporated into the diet without compromising body weight. This has been attributed to strong satiety properties; increased resting energy expenditure; and limited lipid bioaccessibility. OBJECTIVE: The role of mastication was explored because of evidence that the availability of nut lipids is largely dependent on the […]

Successful oral tolerance induction in severe peanut allergy

Background: Peanut allergy is common; potentially severe and rarely resolves causing impaired quality of life. No disease-modifying treatment exists and there is therefore a need to develop a therapeutic intervention. Aims of the study: The aim of this study was to investigate whether peanut oral immunotherapy (OIT) can induce clinical tolerance to peanut protein. Methods: […]