Accuracy of component‐resolved diagnostics in peanut allergy: systematic literature review and meta‐analysis.
Background: Peanut allergy diagnosis relies on clinical reactivity to peanut supported by detection of specific IgE (sIgE) antibodies. Extract-based sIgE tests have low specificity, so component-resolved diagnostics may complement whole extract testing. Methods: We systematically collected peanut allergen component data in seven databases and studied the diagnostic accuracy of peanut storage proteins (Arah1, 2, 3), and cross-reactive […]
Determining Levers of Cost-effectiveness for Screening Infants at High Risk for Peanut Sensitization Before Early Peanut Introduction.
Importance: Early peanut introduction reduces the risk of developing peanut allergy, especially in high-risk infants. Current US recommendations endorse screening but are not cost-effective relative to other international strategies. Objective: To identify scenarios in which current early peanut introduction guidelines would be cost-effective. Design, setting, and participants: This simulation/cohort economic evaluation used microsimulations and cohort analyses in a […]
Dual transcriptomic and epigenomic study of reaction severity in peanut allergic children.
Background: Unexpected allergic reactions to peanut are the most common cause of fatal food-related anaphylaxis. Mechanisms underlying the variable severity of peanut allergic reactions remain unclear. Objectives: To expand mechanistic understanding of reaction severity in peanut allergy. Methods: We performed an integrated transcriptomic and epigenomic study of peanut allergic children as they reacted in vivo during double-blind, placebo-controlled […]
Evaluation of the epidemiology of peanut allergy in the United Kingdom.
Aims: To describe the epidemiology of peanut allergy (PA) in the UK over the last three decades. Methods: PA patients were identified from the Clinical Practice Research Datalink between 1987 and 2015. Incidence and prevalence of PA were compared between 2000 and 2015. Prevalence and relative risk (RR) of atopic comorbidities, anaphylaxis, adrenaline prescriptions versus […]
Undeclared allergens in imported packaged food for retail in Australia.
The Australia New Zealand Food Standards Code (the Code) requires a declaration of the presence of 11 different allergens made through the label on a food product. Most food recalls in Australia are now due to undeclared allergens. This survey determined the extent of undeclared allergens in imported food products on the Asian retail market in Australia. […]
Peanut Oral Immunotherapy: State of the Art.
Cumulative evidence shows that peanut oral immunotherapy (OIT) is effective at inducing desensitization through downregulation of effector pathways in the allergic reaction cascade; however, only a subset of patients achieve sustained unresponsiveness (remission), which requires redirection of the underlying allergic response toward tolerance. A recent meta-analysis of peanut OIT randomized trials found that OIT is […]
Improvement in nutritional quality and thermal stability of palm olein blended with macadamia oil for deep-fat frying application.
Macadamia nut shell (MNS) is a type of waste lignocellulose obtained from macadamia nut production processing. Large MNS wastes caused serious resource waste and environmental pollution. So, preparation of hydrochars from MNS via hydrothermal carbonization (HTC) is of great significance. HTC of MNS was conducted to study the effect of process parameters, including HTC temperature […]
Air and Steam Gasification of Almond Biomass.
Experiments were performed on a laboratory scale fluidized bed gasifier to characterize the gasification products of almond shell and hull removed in nut processing operations and to determine the effect of gasifying media on bed agglomeration. The higher heating value of syngas during air gasification of almond biomass ranged from 4 to 6 MJ m−3 while […]
Managing high fiber food waste for the cultivation of black soldier fly larvae.
Increases in global human population are leading to increasing demands for food production and waste management. Insect biomass is a sustainable alternative to traditional animal feeds when insects are produced on lignocellulosic by-products. Resources high in lignocellulose have high carbon to nitrogen ratios and require nitrogen supplementation to accelerate bioconversion. Here we report on studies […]
Chemical changes in almonds throughout storage: modeling the effects of common industry practices.
Further investigations of almond degradation under typical industrial storage conditions from a quantitative perspective are warranted. This study modeled effects of packaging, temperature (TEMP), relative humidity (RH) and roasting on chemical attributes of almonds stored according to common industry practices throughout 16 months. Roasted samples were stored in high‐barrier bags (HBB) or polypropylene bags (PPB) at […]