Vaccine against peanut allergy based on engineered Virus-Like-Particles displaying single major peanut allergens.
Background: Peanut allergy is a severe and increasingly frequent disease with high medical, psychosocial and economical burden for affected patients. A causal, safe and effective therapy is not available. Objective: We aimed to develop an immunogenic, protective and non-reactogenic vaccine candidate against peanut allergy based on Virus-like Particles (VLPs) coupled to single peanut allergens. Methods: To generate vaccine […]
Real-world tree nut consumption in peanut-allergic individuals.
Background: Individuals with peanut allergy often avoid tree nuts, yet true rates of tree nut allergy in peanut-allergic individuals are as low as 7%. Objective: To examine tree nut sensitization patterns in peanut-allergic individuals, patient and family choice regarding tree nut consumption, and factors that influence consumption of tree nuts. Methods: All patients presenting for […]
Defining challenge-proven coexistent nut and sesame seed allergy: A prospective multicenter European study.
Background: Peanut, tree nut, and sesame allergies are responsible for most life-threatening food-induced allergic reactions. Rates of coexistent allergy between these foods have been from mostly retrospective studies that include only a limited number of tree nuts or were not based on oral food challenges. Objective: The Pronuts study is a multicenter European study (London, […]
Current perspectives on peanut allergy.
Peanut allergy is increasingly prevalent and for most patients is a life-long condition, with the potential to cause life-threatening reactions. Accurate diagnosis and appropriate management are essential to minimise risks due to accidental peanut exposure. Current management strategies focus on strict allergen avoidance and access to emergency medicines to treat potential reactions; however, active approaches […]
Prevention of Non-peanut Food Allergies.
Purpose of review: The purpose of this review article is to discuss the recent literature around methods of prevention of food allergies other than peanut allergy. Recent findings: While the most robust data to date exists for peanut, there are emerging studies suggesting a beneficial effect to early introduction of cooked egg, and cow's milk […]
High sorption efficiency for As (III) and As (V) from aqueous solutions using novel almond shell biochar.
Arsenic (As) presence in surface reservoirs and groundwater is considered as an extremely alarming issue around the globe. The objectives of the present study were to evaluate the sorption potential of almond shell (ALS) and almond shell biochar (ASB) based sorbents for the removal of As(III)/As(V) from As-contaminated aqueous solutions. The maximum As(III) sorption capacity […]
In Vitro Antioxidant Activity Optimization of Nut Shell (Carya Illinoinensis) by Extrusion Using Response Surface Methods.
The pecan (Carya illinoinensis) nut shell is an important byproduct of the food processing industry that has not been previously explored as an antioxidant compound. This work aims to study the effect of the extrusion temperature and screw speed on the moisture content, water and oil absorption index, water solubility index, color, phenolic compounds, condensed […]
Characterization of Polyphenolic Compounds Extracted from Different Varieties of Almond Hulls (Prunus dulcis L.).
Ultrasound-assisted extraction (UAE) was applied as a pretreatment technique to improve the recovery of polyphenols from the almond hulls of four Tunisian and three Italian almond varieties, followed by the characterization with HPLC-DAD. The operating parameters (solid/liquid ratio, extraction time, and ethanol concentrations) were optimized using a Response Surface Methodology. A polynomial equation was calculated […]
Reducing atmosphere drying as a novel drying technique for preserving the sensorial and nutritional notes of foods.
Reducing atmosphere drying (RAD) was assayed as a novel technique for preserving the color and the nutritional fresh notes of apricot. A freeze, hot air and vacuum drying techniques were applied for a comparison purpose. The results showed that the apricot samples dried by both RADMIX and RADNITROGEN preserved better the fresh color notes while the freeze-drying […]
FT-IR spectroscopy and Morphological study of functionalized cellulosic fibers: Evaluation of their dyeing properties using biological Pistacia vera hulls by-product extract.
The repulsion between cellulose and anionic entities could be overcome by imparting cationic sites on its structure. In this work, we studied the treatment of cotton fabric with different amounts of chitosan bio-polymer (0.0125-0.075%), dimethyl diallyl ammonium chloride and diallylamin co-polymer (1-5%), alum (0.5-20 g/L), and sodium chloride (2-40 g/L) in order to improve their […]