Global patterns in anaphylaxis due to specific foods: a systematic review

Background: There are increasing global data relating to prevalence of food allergy and food-induced anaphylaxis, however this is often based on surrogate measures of sensitization rather than objective symptoms at food challenge. In terms of protecting food-allergic consumers from reactions, there has been no global survey assessing geographical differences in the proportion of anaphylaxis triggered […]

Unbiased Immunization Strategy Yielding Specific Nanobodies against Macadamia Allergen of Vicilin-like Protein for Immunoassay Development

Macadamia nut contains important food allergens that potentially cause allergic reactions with severe adverse effects in infants and adults. Reliable and accurate detection of macadamia is critical to avoid allergic reactions. However, knowledge on macadamia allergen is scarce and a reliable detection method has not been reported, yet. In this study, an unbiased immunization and […]

ImmunoCAP ISAC in food allergy diagnosis: a systematic review of diagnostic test accuracy

The aim of this systematic review is to assess the diagnostic test accuracy of the component-resolved diagnosis device ImmunoCAP ISAC, compared with oral food challenge. Systematic review reported according to the PRISMA-DTA recommendations. Medline, Embase and Cochrane Library databases were searched from inception to May 2019 and updated in March 2021. We included diagnostic test […]