The randomized controlled trial compared a-LCD with a low-fat diet (LFD). A total of 45 participants were involved in the study with 22 people in the a-LCD group and 23 in the LFD group. The indicators for depression and glycosylated hemoglobin (HbA1c) were significantly improved for those participants in the a-LCD group. Moreover, a-LCD increased the short chain fatty acid-producing bacteria Roseburia, Ruminococcus and Eubacterium.
 
In conclusion, an almond-based low carbohydrate diet may provide a beneficial effect on depression and glycometabolism in patients with type 2 diabetes. The researchers suggest that more research should focus on the short chain fatty acid-producing bacteria.
 
Ren, M., Zhang, H., Qi, J., Hu, A., Jiang, Q., Hou, Y., … & Wang, X. (2020). An almond-based low carbohydrate diet improves depression and glycometabolism in patients with Type 2 Diabetes through modulating gut microbiota and GLP-1: A randomized controlled trial. Nutrients, 12(10), 3036.

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