The component-specific to total IgE ratios do not improve peanut and hazelnut allergy diagnoses.
BACKGROUND: Specific IgE measurement predicts the outcome of oral food challenges with considerable uncertainty when evaluating food allergy. OBJECTIVE: Our aim was to assess whether accounting for the ratio of component- or allergen-specific to total IgE can improve this prediction. METHODS: This multicenter study collected blood samples from children with suspected peanut or hazelnut allergy […]
Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects
Jug r 2-reactive CD4+ T cells have a dominant immune role in walnut allergy.
Administration of a probiotic with peanut oral immunotherapy: A randomized trial
Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice
Identification of hazelnut major allergens in sensitive patients with positive double-blind, placebo-controlled food challenge results
Hazelnut allergy: A double-blind, placebo-controlled food challenge multicenter study
Peanut and tree nut consumption during pregnancy and allergic disease in children—should mothers decrease their intake? Longitudinal evidence from the Danish National Birth Cohort
Background: The relation between maternal peanut intake during pregnancy and allergic disease development in children has been controversial. Objective: We used data from the Danish National Birth Cohort to examine associations between maternal peanut and tree nut intake during pregnancy and allergic outcomes in children at 18 months and 7 years of age. Methods: We […]
The eliciting dose of peanut in double-blind; placebo-controlled food challenges decreases with increasing age and specific IgE level in children and young adults.
Background: Several risk factors for severe anaphylactic reactions to food in daily life are known. However; to date; it is not possible to predict the severity of allergic reactions to food in the individual patient with accuracy. Some studies show that a history of severe reactions is associated with a lower eliciting dose in double-blind; […]
A randomized controlled study of peanut oral immunotherapy: Clinical desensitization and modulation of the allergic response
Abstract BACKGROUND: Open-label oral immunotherapy (OIT) protocols have been used to treat small numbers of patients with peanut allergy. Peanut OIT has not been evaluated in double-blind; placebo-controlled trials. OBJECTIVE: To investigate the safety and effectiveness of OIT for peanut allergy in a double-blind; placebo-controlled study. METHODS: In this multicenter study; children ages 1 to […]