Tolerance of peanuts and tree nuts in Spanish children with exclusive sensitization to lipid transfer proteins
Background: Allergy to peanuts and tree nuts is a common cause of food allergy in Spain, with lipid transfer proteins (LTP) being the most frequently recognized panallergen. LTP sensitization often leads to multiple food group sensitivities, resulting in overly restrictive diets that hinder patient’s quality of life. This study aimed to assess the tolerance of […]
Current options in the management of tree nut allergy: A systematic review and narrative synthesis
Tree nut allergy is a lifelong and potentially life-threatening condition. The standard of care is strictly avoiding the culprit nut and treating accidental reactions symptomatically. To evaluate potential therapeutic options for desensitizing patients with IgE-mediated tree nut allergy, we systematically searched three bibliographic databases for studies published until January 2024. We looked for active treatments […]
Design of the Intervention to Reduce Early Peanut Allergy in Children (iREACH): A practice-based clinical trial
Background: Introducing peanut products early can prevent peanut allergy (PA). The “Addendum guidelines for the prevention of PA in the United States” (PPA guidelines) recommend early introduction of peanut products to low and moderate risk infants and evaluation prior to starting peanut products for infants at high risk for PA (those with severe eczema and/or […]
Food allergen introduction patterns in the first year of life: A US nationwide survey.
Background: Prevention guidelines have changed over the past decade and now recommend the earlier introduction of peanut and egg without delaying the introduction of other food allergens. This paper explored caregiver practices regarding the introduction of food allergens during infancy. Methods: A survey was administered (2021) to a US population-based sample of 3062 caregivers (children […]
Macadamia nut-specific IgE levels for predicting anaphylaxis.
Background: Despite the high risk of anaphylaxis in patients with a macadamia nut allergy (MdA), little is known about the significance of macadamia nut-specific immunoglobulin E (Md-sIgE). Thus, this study aimed to investigate the utility of Md-sIgE for predicting anaphylaxis. Methods: Children with suspected MdA who visited our hospital were included. MdA was defined as […]
Oleosin Cor a 15 is a novel allergen for Italian hazelnut allergic children.
Background. Hazelnut allergy, which is characterized by symptoms that range from mild to severe, is one of the most common allergies in children throughout Europe, and an accurate diagnosis of this allergy is therefore essential. However, lipophilic allergens, such as oleosins, are generally underrepresented in diagnostic tests. We therefore sought to characterize the IgE reactivity […]
Parental Intentions Regarding Introduction of Common Food Allergens During Complimentary Feeding
Food allergy affects 5-6% of Irish children with 3-6% of preschool children affected. Common food allergens in preschool children are milk, egg and peanut while peanut, tree-nut, fish and shellfish allergies are more common in older children1. Recent studies such as LEAP2 and EAT3 reported that regular consumption of common allergy associated foods early in […]
Macadamia nut allergy in children: clinical features and cross-reactivity with walnut
Macadamia nuts, the seeds of Macadamia tetraphylla or Macadamia integrifolia of family Proteaceae, are a familiar food item. Previous case reports of macadamia nut allergy demonstrated the possibility of false negative IgE antibody test results and cross-reactivity of macadamia nut with hazelnut. However, the clinical features of childhood macadamia nut allergy and the cross-reactivity of […]
Impact of age on adherence and efficacy of peanut oral‐immunotherapy using a standardized protocol.
Impact of age on adherence and efficacy of peanut oral-immunotherapy using a standardized protocol.
Peanut oral immunotherapy (POIT) has been shown to be an effective therapy in peanut allergic children, as it improves food allergy-related quality of life [1-2] . Randomized controlled trials and observational, real world studies have shown that POIT may be effective and safe in children of all ages, although starting POIT at a younger age may be […]