COR a 14- Specific IgE Predicts symptomatic hazelnut allergy in children.
The self-reported prevalence of tree nut allergy in children has been increasing in the past decade (1). Hazelnuts are in particularly widespread use and this makes them difficult to avoid completely. It is therefore important to correctly diagnose hazelnut allergy to avoid any unjustified diet. The aim of the present study was to assess the […]
Food allergic infants have impaired regulatory T cell responses following in vivo allergen exposure
BACKGROUND: Regulatory T cells (Tregs) are critical for development of oral tolerance, and studies suggest that dysfunction of Tregs may lead to food allergy. However to date no study has investigated Treg responses following in vivo exposure to peanut or egg allergens in humans. OBJECTIVES: To examine changes in peripheral blood CD4+ CD25+ FoxP3+ Treg […]
Sensitisation to milk, egg and peanut from birth to 18 years: a longitudinal study of a cohort at risk of allergic disease
BACKGROUND: Longitudinal data on the natural history of food sensitisation beyond early childhood are scarce. We aimed to investigate the natural history of milk, egg and peanut sensitisation from infancy to18 years and assess whether early food sensitisation predicted adolescent food allergy. METHODS: Sensitisation to cow's milk, hen's egg and peanut was measured by skin […]
Outcome of mixed nut biscuit challenges in low risk patients who are on tree nut exclusion diet.
Ara h 2 and Ara h 6 sensitization predict peanut allergy in Mediterranean pediatric patients
Management of nut allergy influences quality of life and anxiety in children and their mothers
Nut allergy is known to impact on the quality of life (QoL) and anxiety of both the allergic child and their parents; but little is known about how the management of food allergy is associated with these variables. To investigate the impact of nut allergy on QoL and anxiety in mothers and children with nut […]
Combining skin prick; immediate skin application and specific-IgE testing in the diagnosis of peanut allergy in children
Previous studies have suggested various diagnostic cut-offs of allergy tests for the diagnosis of clinical peanut allergy in children. There are few data relating to the use of combinations of these tests in children. We aimed to determine the validity of previously reported diagnostic cut-off levels of peanut allergen skin tests and peanut specific-immunoglobulin (Ig) […]