Cashew Oral Immunotherapy for Desensitizing Cashew-Pistachio Allergy (Nut CRACKER Study)

  Background: Oral immunotherapy (OIT) is a treatment option for patients with milk, egg and peanut allergy, but data on the efficacy and safety of cashew OIT is limited. Methods: A cohort of 50 cashew-allergic patients aged ≥4 years, who were consecutively enrolled into cashew OIT (target dose 4000 mg protein) between 4/2016-12/2019. Fifteen cashew-allergic patients who […]

Spatial lipidomics of eight edible nuts by desorption electrospray ionization with ion mobility mass spectrometry imaging

Nuts have long been known for their health benefits which are mainly contributed by their lipid components. However, the spatial distribution of lipids in nuts has not been firmly established. In this study, desorption electrospray ionization combined with ion mobility and quadrupole time-of-flight mass spectrometry in positive and negative ion modes was applied to visualize […]

Cashew nut shell liquids: Antimicrobial compounds in prevention and control of the oral biofilms.

Objective: The aim was to evaluate the antibacterial and antibiofilm activity of natural (n-CNSL) and technical (t-CNSL) cashew nut shell liquid against streptococci and enterococci related to dental caries and chronic apical periodontitis, respectively. Material and methods: Minimum inhibitory concentrations (MIC) and minimal bactericidal concentration (MBC) were determined to assess the antimicrobial effect of both […]

Cashew nut shell liquids: Antimicrobial compounds in prevention and control of the oral biofilms.

Objective: The aim was to evaluate the antibacterial and antibiofilm activity of natural (n-CNSL) and technical (t-CNSL) cashew nut shell liquid against streptococci and enterococci related to dental caries and chronic apical periodontitis, respectively.   Material and methods: Minimum inhibitory concentrations (MIC) and minimal bactericidal concentration (MBC) were determined to assess the antimicrobial effect of […]

Modulatory effect of cashew (Anacardium occidentale L.) nut supplemented diet on fertility activity of clomiphene citrate in male rats.

Background: Increasing concern has been expressed about the declining sperm count of humans and the potential fertility effects of clomiphene citrate, a synthetic oestrogen-antagonist on human reproductive health in the last few decades. This study aims to investigate the influence of cashew nut supplemented diet on fertility activity of clomiphene citrate in male rats. Methods: […]

Cashew Nut Shell Liquid (CNSL) as a Source of Drugs for Alzheimer’s Disease.

Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a multifaceted pathogenesis. This fact has long halted the development of effective anti-AD drugs. Recently, a therapeutic strategy based on the exploitation of Brazilian biodiversity was set with the aim of discovering new disease-modifying and safe drugs for AD. In this review, we will illustrate our […]

Preparation and in vitro bioactive evaluation of cashew-nut proteins hydrolysate as a potential source of anti-allergy peptides.

This work proposes a novel potential source of antiallergens based on bioactive peptides. Cashew-nut protein hydrolysate with antiallergic activity was prepared from cashew nuts through protease treatment. The change in the antiallergic activity of cashew-nut protein hydrolysate during in vitro simulated digestion was investigated. Cashew-nut protein hydrolysates were prepared through treatment using five different enzymes, […]

Acute consumption of a shake containing cashew and Brazil nuts did not affect appetite in overweight subjects: a randomized, cross-over study.

Purpose. Evidence from epidemiological and clinical studies suggests that nut consumption provides satiety and may contribute to the management of obesity. However, the effect of acute intake of nuts on appetite responses remains unclear. The objective of this study was to evaluate the acute effect of a shake containing 30 g of cashew nuts (Anacardium […]