A total of twenty-seven postmenopausal women were included in this crossover study. Participants were asked to consume six prunes (∼42 g) or two (∼14 g) per day for 2 weeks, after a 2-week washout period, then they crossed over and consumed the other amount of prunes. Serum C-telopeptide, beta-crosslinked (CTX) was used as a measure of bone resorption. Peripheral artery tonometry (PAT) was used to assess microvascular function. The study results observed that participants who consumed six prunes per day experimented a trend in CTX reduction (a decrease in bone resorption).
Al-Dashti, Y.A., Holt, R.R., Carson, J.G., Keen, C.L., Hackman, R.M. (2019). Effects of Short-Term Dried Plum (Prune) Intake on Markers of Bone Resorption and Vascular Function in Healthy Postmenopausal Women: A Randomized Crossover Trial. Journal of Medicinal Food, doi: 10.1089/jmf.2018.0209.
Al-Dashti, Y.A., Holt, R.R., Carson, J.G., Keen, C.L., Hackman, R.M. (2019). Effects of Short-Term Dried Plum (Prune) Intake on Markers of Bone Resorption and Vascular Function in Healthy Postmenopausal Women: A Randomized Crossover Trial. Journal of Medicinal Food, doi: 10.1089/jmf.2018.0209.