Successful oral tolerance induction in severe peanut allergy
Background: Peanut allergy is common; potentially severe and rarely resolves causing impaired quality of life. No disease-modifying treatment exists and there is therefore a need to develop a therapeutic intervention. Aims of the study: The aim of this study was to investigate whether peanut oral immunotherapy (OIT) can induce clinical tolerance to peanut protein. Methods: […]
Clinical Features of Four Cases with Cashew Nut Allergy and Cross-Reactivity between Cashew Nut and Pistachio
Background: Few cases of cashew nut (CN) allergy have been reported in Japan. We evaluated the clinical features of 4 cases with CN allergy and investigated the allergens involved. Methods: In order to investigate the cross-reactivity between CN and pistachios; we performed ImmunoCAP inhibition tests using sera of 4 cases with positive histories of CN […]
Effects of processing on immunoreactivity of cashew nut (Anacardium occidentale L.) seed flour proteins
Cashew nut seeds were subjected to processing including autoclaving (121 degrees C for 5; 10; 20; and 30 min); blanching (100 degrees C for 1; 4; 7; and 10 min); microwave heating (1 and 2 min each at 500 and 1000 W); dry roasting (140 degrees C for 20 and 30 min; 170 degrees C […]
Tree nut and peanut consumption in relation to chronic and metabolic diseases including allergy
The New and Emerging Research session highlighted the emerging understanding of both the positive and negative effects of nuts consumption on health. The limited nature of both experimental and epidemiological evidence for positive relationship(s) between nut intake and health were noted. Study inconsistency and limitations; particularly survey methodology; were explored. Recent results from epidemiologic studies […]
Tree Nut and Peanut Consumption in Relation to Chronic and Metabolic Diseases Including Allergy
The New and Emerging Research session highlighted the emerging understanding of both the positive and negative effects of nuts consumption on health. The limited nature of both experimental and epidemiological evidence for positive relationship(s) between nut intake and health were noted. Study inconsistency and limitations; particularly survey methodology; were explored. Recent results from epidemiologic studies […]
In vivo and T Cell Cross-Reactivity between Walnut; Cashew and Peanut
Background: Examination of IgE cross-reactivity among nuts has been limited to in vitro experiments. Cross-reactivity studies of nuts at the T cell level are difficult to interpret because of the inability to determine which cellular responses are from a true sensitization and which are due to cross-reactivity. Using a mouse model in which the sensitizing […]
Approaches to establish thresholds for major food allergens and for gluten in food
Walnut allergens.
Dietary assessment in children adhering to a food allergen avoidance diet for allergy prevention.
Objective: The purpose of this investigation was to verify if avoidance of allergenic foods in children adhering to a food allergen avoidance diet from birth was complete and feasible; and whether dietary assessment can be used as a tool in predicting the outcome of double-blind; placebo-controlled food challenges (DBPCFCs). Design: Children adhering to an allergen […]
Combining skin prick; immediate skin application and specific-IgE testing in the diagnosis of peanut allergy in children
Previous studies have suggested various diagnostic cut-offs of allergy tests for the diagnosis of clinical peanut allergy in children. There are few data relating to the use of combinations of these tests in children. We aimed to determine the validity of previously reported diagnostic cut-off levels of peanut allergen skin tests and peanut specific-immunoglobulin (Ig) […]