Manganese Blocks Intracellular Trafficking of Shiga Toxin and Protects Against Shiga Toxicosis

Infections with Shiga toxin (STx)–producing bacteria cause more than a million deaths each year and have no definitive treatment. To exert its cytotoxic effect; STx invades cells through retrograde membrane trafficking; escaping the lysosomal degradative pathway. We found that the widely available metal manganese (Mn2+) blocked endosome-to-Golgi trafficking of STx and caused its degradation in […]

Hexavalent chromium removal from aqueous medium by activated carbon prepared from peanut shell: Adsorption kinetics; equilibrium and thermodynamic studies

Activated carbon was prepared from peanut shell by chemical activation with KOH. Unoxidized activated carbon was prepared in nitrogen atmosphere which was then heated in air at a desired temperature to get oxidized activated carbon. The prepared carbons were characterized for surface area and pore volume and utilized for the removal of Cr(VI) from aqueous […]