The glycemic effect of nut-enriched meals in healthy and diabetic subjects
BACKGROUND AND AIMS: The intake of nuts has been linked to a reduced risk of cardiovascular disease (CVD) and diabetes in large cohort studies. One potential contributing mechanism may be the ability of nuts to improve post-meal glycemic response. We; therefore; examined the effect of nuts alone and in combination with white bread on postprandial […]
Current guidelines for nut consumption are achievable and sustainable: a hazelnut intervention
Nuts are known for their hypocholesterolaemic properties; however; to achieve optimal health benefits; nuts must be consumed regularly and in sufficient quantity. It is therefore important to assess the acceptability of regular consumption of nuts. The present study examined the long-term effects of hazelnut consumption in three different forms on 'desire to consume' and 'overall […]
Effect of a traditional Mediterranean diet on apolipoproteins B; A-I; and their ratio. A randomized; controlled; trial
Objectives: Apolipoprotein (Apo)B; ApoA-I; and their ratio could predict coronary heart disease (CHD) risk more accurately than conventional lipid measurements. Our aim was to assess the effect of a traditional Mediterranean diet (TMD) on apolipoproteins. Methods: High-cardiovascular risk subjects (n =551; 308 women and 243 men); aged 55 to 80; were recruited into a large; […]
Influence of body mass index and serum lipids on the cholesterol-lowering effects of almonds in free-living individuals
BACKGROUND AND AIMS: Short-term (4-9 weeks) human feeding trials have shown nut consumption to reduce serum total cholesterol (TC) and LDL-cholesterol (LDL). We hypothesized that individual levels of BMI; LDL; TC and triglycerides modify the cholesterol-lowering effect of almonds in a 24-week almond supplementation trial in a free-living population. METHODS AND RESULTS: We performed secondary […]
Effect of roasting on phenolic content and antioxidant activities of whole cashew nuts; kernels; and testa
The effect of roasting on the content of phenolic compounds and antioxidant properties of cashew nuts and testa was studied. Whole cashew nuts; subjected to low-temperature (LT) and high-temperature (HT) treatments; were used to determine the antioxidant activity of products. Antioxidant activities of cashew nut; kernel; and testa phenolics extracted increased as the roasting temperature […]
Food Grade Fungal Stress on Germinating Peanut Seeds Induced Phytoalexins and Enhanced Polyphenolic Antioxidants
The effects of food grade fungus Rhizopus oligosporus stress on phytochemicals and phytoalexins of germinating peanut seeds were investigated by comparing the metabolic profiles of ungerminated (UG); germinated (G); and germinated seeds under fungal stress (GS). Three types of peanut seeds with different skin color (red; reddish brown; and black) were compared in the process. […]
Antiproliferative and antioxidant activities of Juglans regia fruit extracts
Cancer chemopreventive action of walnut [Juglans regia L. (Juglandaceae)] has been explored. Objective: This study evaluated antiproliferative and antioxidant activities of walnut. Materials and methods: Various fractions of walnut extract have been screened for antiproliferative activity against human cancer cell lines using the MTT assay. All these fractions have also been evaluated for total phenolic […]
Anti-proliferative Effects of Organic Extracts from Root Bark of Juglans Regia L. (RBJR) on MDA-MB-231 Human Breast Cancer Cells: Role of Bcl-2/Bax; Caspases and Tp53
With increasing use of plant-based cancer chemotherapeutic agents; exploring the antiproliferative effects of phytochemicals has gained increasing momentum for anticancer drug design. The present study was undertaken to investigate the effect of root bark of Juglans regia (RBJR) organic extracts on cell proliferation; and to determine the molecular mechanism of RBJR-induced cell death by determining […]
Foods and Food Groups Associated With the Incidence of Colorectal Polyps: The Adventist Health Study
Colorectal cancer (CRC) is a leading cause of cancer death in the United States. The majority of CRC arise in adenomatous polyps and 25-35% of colon adenoma risk could be avoidable by modifying diet and lifestyle habits. We assessed the association between diet and the risk of self-reported physician-diagnosed colorectal polyps among 2;818 subjects who […]
Immunomagnetic bead-based recovery and real time quantitative PCR (RT iq-PCR) for sensitive quantification of aflatoxin B
Aflatoxin B1 is an unavoidable natural mycotoxin that enters the food chain by contamination of food grains and feedstuffs; potentially posing carcinogenic risks to animal and human health. Immuno-PCR methods have the potential to address the need of meeting the regulatory limits by detecting trace levels of toxins present in food and animal feeds. This […]