Influence of body mass index and serum lipids on the cholesterol-lowering effects of almonds in free-living individuals
BACKGROUND AND AIMS: Short-term (4-9 weeks) human feeding trials have shown nut consumption to reduce serum total cholesterol (TC) and LDL-cholesterol (LDL). We hypothesized that individual levels of BMI; LDL; TC and triglycerides modify the cholesterol-lowering effect of almonds in a 24-week almond supplementation trial in a free-living population. METHODS AND RESULTS: We performed secondary […]
Effect of roasting on phenolic content and antioxidant activities of whole cashew nuts; kernels; and testa
The effect of roasting on the content of phenolic compounds and antioxidant properties of cashew nuts and testa was studied. Whole cashew nuts; subjected to low-temperature (LT) and high-temperature (HT) treatments; were used to determine the antioxidant activity of products. Antioxidant activities of cashew nut; kernel; and testa phenolics extracted increased as the roasting temperature […]
Food Grade Fungal Stress on Germinating Peanut Seeds Induced Phytoalexins and Enhanced Polyphenolic Antioxidants
The effects of food grade fungus Rhizopus oligosporus stress on phytochemicals and phytoalexins of germinating peanut seeds were investigated by comparing the metabolic profiles of ungerminated (UG); germinated (G); and germinated seeds under fungal stress (GS). Three types of peanut seeds with different skin color (red; reddish brown; and black) were compared in the process. […]
Antiproliferative and antioxidant activities of Juglans regia fruit extracts
Cancer chemopreventive action of walnut [Juglans regia L. (Juglandaceae)] has been explored. Objective: This study evaluated antiproliferative and antioxidant activities of walnut. Materials and methods: Various fractions of walnut extract have been screened for antiproliferative activity against human cancer cell lines using the MTT assay. All these fractions have also been evaluated for total phenolic […]
Anti-proliferative Effects of Organic Extracts from Root Bark of Juglans Regia L. (RBJR) on MDA-MB-231 Human Breast Cancer Cells: Role of Bcl-2/Bax; Caspases and Tp53
With increasing use of plant-based cancer chemotherapeutic agents; exploring the antiproliferative effects of phytochemicals has gained increasing momentum for anticancer drug design. The present study was undertaken to investigate the effect of root bark of Juglans regia (RBJR) organic extracts on cell proliferation; and to determine the molecular mechanism of RBJR-induced cell death by determining […]
Effect of phytochemical concentrations on biological activities of Cranberry extracts.
Abstract: Plants of cranberry (Vaccinium macrocarpon) furnish edible fruits and derivates that have been used for the prevention and treatment of urinary tract infections. In the present work we compare two commercial extracts that contain proanthocyanins (PACs) at 4 percent and 20 percent for antimicrobial; antiproliferative; antiradical and protective properties against oxidative stress on cell […]
Phytochemical and antioxidant properties of selected fig (Ficus carica L.) accessions from the eastern Mediterranean region of Turkey.
Abstract: Fig has been a typical fruit component of the health-promoting Mediterranean diet for a very long time. Phytochemical characters and antioxidant capacity of green-; yellow-; brown-; purple-; and black-fruited fig (Ficus carica L.) accessions were investigated. In this study; total phenolics (TP); total anthocyanins (TA); fructose (FRUC); glucose (GLUC); sucrose (SUC); and variables (such […]
Glycemic and insulinemic responses to different preexercise snacks in participants with impaired fasting glucose.
PURPOSE: To compare serum glucose and insulin responses to 3 preexercise snacks before; during; and after exercise in individuals with impaired fasting glucose (IFG) and healthy (H) men. In addition; in an IFG population; the authors sought to determine whether a natural fruit snack (i.e.; raisins) yields more desirable glucose and insulin concentrations than an […]
Cranberry Proanthocyanidins Mediate Growth Arrest of Lung Cancer Cells through Modulation of Gene Expression and Rapid Induction of Apoptosis.
Abstract: Cranberries are rich in bioactive constituents purported to enhance immune function; improve urinary tract health; reduce cardiovascular disease and more recently; inhibit cancer in preclinical models. However; identification of the cranberry constituents with the strongest cancer inhibitory potential and the mechanism associated with cancer inhibition by cranberries remains to be elucidated. This study investigated […]
Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions
Abstract: Diet plays a seminal role in the prevention and treatment of cardiovascular disease. Consumption of tree nuts has been shown to reduce low-density lipoprotein cholesterol (LDL-C); a primary target for coronary disease prevention; by 3-19%. Almonds have been found to have a consistent LDL-C-lowering effect in healthy individuals; and in individuals with high cholesterol […]