Development of a Buccal tablets for Curcumin using Anacardium occidentale Gum
The objective of the present investigation was to develop uni-directional, bilayered, buccoadhesive tablets of curcumin using a natural buccoadhesive polymer cashew nut tree gum along with ethyl cellulose as an impermeable backing layer. A batch prepared with 20% polymer concentration, 0.1% penetration enhancer, 40 mg backing layer, compressed at 2 tons/cm2 for 10 sec was […]
Manganese Blocks Intracellular Trafficking of Shiga Toxin and Protects Against Shiga Toxicosis
Infections with Shiga toxin (STx)Âproducing bacteria cause more than a million deaths each year and have no definitive treatment. To exert its cytotoxic effect; STx invades cells through retrograde membrane trafficking; escaping the lysosomal degradative pathway. We found that the widely available metal manganese (Mn2+) blocked endosome-to-Golgi trafficking of STx and caused its degradation in […]
Evaluation of the total phenolics and quercetin content of foliage in mycorrhizal grape (Vitis vinifera L.) varieties and effect of postharvest drying on quercetin yield
Hexavalent chromium removal from aqueous medium by activated carbon prepared from peanut shell: Adsorption kinetics; equilibrium and thermodynamic studies
Activated carbon was prepared from peanut shell by chemical activation with KOH. Unoxidized activated carbon was prepared in nitrogen atmosphere which was then heated in air at a desired temperature to get oxidized activated carbon. The prepared carbons were characterized for surface area and pore volume and utilized for the removal of Cr(VI) from aqueous […]
Comparison of gastric ulcerogenicity of percolated extract of Anacardium occidentale (Cashew Nut) with indomethacin in rats
In traditional Iranian medicine; the core of the fruit of Anacardium occidentale (cashew nut) has been used in the management of the pain. In this study gastric ulcerogenicity effect of the percolated extract of A. occidentale was investigated in rats. The extract or indomethacin (200; 300; 400 and 800 mg/kg) was administrated orally. In the […]
Cancer chemoprevention by nuts: evidence and promises
Chemoprevention is the use of chemical compounds to interfere with the early precancerous stages of carcinogenesis and thereby reverse tumor formation. Many chemopreventive agents; either natural or synthetic; have been identified. Some of the most promising compounds are found in vegetables and fruits. There are numerous mechanisms of action by which these components can intervene […]
Dietetic benefits associated with the regular intake of moderate amounts of naturally-occurring phytosterols
Effect of Brazil Nut Supplementation on Plasma Levels of Selenium in Hemodialysis Patients: 12 Months of Follow-up
Background: Large amounts of reactive oxygen species are produced in hemodialysis (HD) patients; and; at higher concentrations; reactive oxygen species are thought to be involved in the pathogenesis of cardiovascular disease. It has been proposed that selenium (Se) may exert an antiatherogenic influence by reducing oxidative stress. The richest known food source of Se is […]
Optimizing the removal of fluoride from water using new carbons obtained by modification of nut shell with a calcium solution from egg shell
Carbons loaded with specific chemical moieties were prepared from pecan nut shells employing a natural modifier agent obtained from egg shell; which is rich in calcium; for the selective adsorption of fluoride from water. A L4 orthogonal array of the Taguchi method was used to optimize the synthesis conditions for obtaining these selective carbons. The […]
Dietary patterns and bone mineral status in young adults: the Northern Ireland Young Hearts Project
Studies of individual nutrients or foods have revealed much about dietary influences on bone. Multiple food or nutrient approaches; such as dietary pattern analysis; could offer further insight but research is limited and largely confined to older adults. We examined the relationship between dietary patterns; obtained by a posteriori and a priori methods; and bone […]