Boiling and roasting treatment affecting the peanut allergenicity.

BACKGROUND: Peanut allergy appears to be less prevalent in other parts of the world than North America and several European countries, and it has been proposed difference in cooking practices may be responsible. In this study, the boiling and roasting processes were investigated to find a potential method to enhanced or reduce the allergenicity. METHODS: […]

IgE Cross-Reactivity of Cashew Nut Allergens.

BACKGROUND: Allergic sensitisation towards cashew nut often happens without a clear history of eating cashew nut. IgE cross-reactivity between cashew and pistachio nut is well described; however, the ability of cashew nut-specific IgE to cross-react to common tree nut species and other Anacardiaceae, like mango, pink peppercorn, or sumac is largely unknown. OBJECTIVES: Cashew nut […]

Effects of thermal treatment on walnut detection and allergenicity.

BACKGROUND: Peanuts and tree nut allergies pose an increasing food safety problem. The aim of our study was to test the accuracy of different commercial ELISA kits in the detection of the presence of walnuts in untreated and heat exposed food samples. The evaluation of the effects of thermal treatment in samples was tested exposing […]

Rapidly detecting major peanut allergen-Ara h2 in edible oils using a new immunomagnetic nanoparticle-based lateral flow assay.

Ara h2 is a major peanut allergen that induces rashes, vomiting, diarrhea, and anaphylactic shock. Since peanut is a major source in producing edible oils globally, Ara h2 residues can be present in various edible oils. In this work, an immunomagnetic nanoparticle-based lateral flow assay for identifying Ara h2 in edible oils is developed. This assay exhibits high sensitivity […]

Long-term Outcome of Peanut Oral Immunotherapy Facilitated Initially by Omalizumab.

BACKGROUND: We successfully used omalizumab to faciliate peanut oral immunotherapy (OIT) in children with reactivity to ≤50mg peanut protein and with high peanut-IgE (median 229 kU/L). OBJECTIVE: We report on long-term OIT outcomes in these patients, including dosing changes, adverse events, peanut immunoglobulin changes and quality of life (QoL). METHODS: Patients were followed for up […]

Early introduction of foods to prevent food allergy.

Food allergy is a growing public health problem, and in many affected individuals, the food allergy begins early in life and persists as a lifelong condition (e.g., peanut allergy). Although early clinical practice guidelines recommended delaying the introduction of peanut and other allergenic foods in children, this may have in fact contributed to the dramatic increase in the prevalence […]

Peanut allergy–individual molecules as a key to precision medicine.

Peanut allergy is one of the most severe food allergies affecting millions of individuals worldwide. In German-speaking countries, peanutallergy is the most important cause of anaphylaxis in children and adolescents. This Editorial highlights the impact of individual peanutallergens on the severity of symptoms and summarizes the allergens' biological characteristics and usefulness as tools for precision diagnostic tests.

Food Allergy: A Comprehensive Population-Based Cohort Study.

OBJECTIVE: To determine the incidence and temporal trends of food allergies. PATIENTS AND METHODS: We performed a historical cohort study to describe the epidemiology of food allergies among residents of all ages in Olmsted County, Minnesota, during a 10-year period from January 2, 2002, through December 31, 2011, using the Rochester Epidemiology Project database. Overall […]