Cell proliferation inhibitory and apoptosis inducing properties of anacardic acid and lunasin in human breast cancer MDA-MB-231 cells

The combination of two or more chemopreventive agents is currently being used to inhibitory effects on breast cancer cells. Anacardic acid and lunasin are two plant-derived compounds that have been associated with anti-carcinogenic properties. These compounds show inhibitory effects on cell proliferation and inducing properties of apoptosis in human breast cancer MDA-MB-231 cell line. Both […]

Cancer Prevention with Natural Compounds

Botanical and nutritional compounds have been used for the treatment of cancer throughout history. These compounds also may be useful in the prevention of cancer. Population studies suggest that a reduced risk of cancer is associated with high consumption of vegetables and fruits. Thus; the cancer chemopreventive potential of naturally occurring phytochemicals is of great […]

The uses and properties of almond oil

Almond oil [Oleum amygdalae] has long been used in complementary medicine circles for its numerous health benefits. Although no conclusive scientific data exists currently; almonds and almond oil have many properties including anti-inflammatory; immunity-boosting and anti-hepatotoxicity effects. Further; associations between almond oil and improved bowel transit have been made; which consequently reduces irritable bowel syndrome […]

Body fat and poor diet in breast cancer women

Background: Breast cancer is the most common cancer in women worldwide. Differences in breast cancer incidence suggest a significant role of environmental factors in the aetiology: obesity; central adiposity; excess body fat and some dietary factors have been suggested as risk factors. This pilot study aimed to analyse the pattern of nutritional status; body fat; […]

Intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease

OBJECTIVE: We examined the association between adolescent fiber intake and proliferative BBD; a marker of increased breast cancer risk; in the Nurses' Health Study II. METHODS: Among 29;480 women who completed a high school diet questionnaire in 1998; 682 proliferative BBD cases were identified and confirmed by centralized pathology review between 1991 and 2001. Multivariate-adjusted […]

Effect of nut consumption on oxidative stress and the endothelial function in metabolic syndrome

BACKGROUND & AIMS: Oxidative stress has a key role in atherosclerosis; cancer and other chronic diseases. Some bioactive compounds in nuts have been implicated in antioxidant activities. OBJECTIVE: We assessed how nut consumption affected several markers of oxidation and endothelial function (EF) in metabolic syndrome (MetS) patients. PATIENTS AND METHODS: A randomized; controlled; parallel feeding […]

Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study

BACKGROUND: The Mediterranean dietary pattern is believed to protect against cancer; although evidence from cohort studies that have examined particular cancer sites is limited. OBJECTIVE: We aimed to explore the association between adherence to a relative Mediterranean diet (rMED) and incident gastric adenocarcinoma (GC) within the European Prospective Investigation into Cancer and Nutrition study. DESIGN: […]

Human cancer cell antiproliferative and antioxidant activities of Juglans regia L.

Several studies suggest that regular consumption of nuts; mostly walnuts; may have beneficial effects against oxidative stress mediated diseases such as cardiovascular disease and cancer. Walnuts contain several phenolic compounds which are thought to contribute to their biological properties. The present study reports the total phenolic contents and antioxidant properties of methanolic and petroleum ether […]